Life‐threatening dystonia–dyskinesias in a child: Successful treatment with bilateral pallidal stimulation
Identifieur interne : 004A37 ( Main/Exploration ); précédent : 004A36; suivant : 004A38Life‐threatening dystonia–dyskinesias in a child: Successful treatment with bilateral pallidal stimulation
Auteurs : Lucia Angelini [Italie] ; Nardo Nardocci [Italie] ; Margherita Estienne [Italie] ; Chiara Conti [Italie] ; Ivano Dones [Italie] ; Giovanni Broggi [Italie]Source :
- Movement Disorders [ 0885-3185 ] ; 2000-09.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Enfant.
English descriptors
- KwdEn :
- Adolescent, Bilateral, Case study, Child, Cognition Disorders (etiology), Critically ill, Deep brain stimulation, Diagnosis, Differential, Dysarthria (etiology), Dyskinesia, Dyskinesias (etiology), Dystonia, Dystonic Disorders (complications), Dystonic Disorders (physiopathology), Dystonic Disorders (therapy), Electric Stimulation Therapy (methods), Electrical stimulus, Electrodes, Implanted, Evolution, Globus Pallidus (surgery), Humans, Instrumentation therapy, Male, Pallidal stimulation, Pallidum, Refractory, Refractory dyskinesia, Refractory dystonia, Severity of Illness Index, Stereotaxic Techniques, Treatment Outcome, Videotape Recording.
- MESH :
- complications : Dystonic Disorders.
- etiology : Cognition Disorders, Dysarthria, Dyskinesias.
- methods : Electric Stimulation Therapy.
- physiopathology : Dystonic Disorders.
- surgery : Globus Pallidus.
- therapy : Dystonic Disorders.
- Adolescent, Diagnosis, Differential, Electrodes, Implanted, Humans, Male, Severity of Illness Index, Stereotaxic Techniques, Treatment Outcome, Videotape Recording.
Abstract
We report a 13‐year‐old boy who developed severe, refractory dystonia–dyskinesias as an abrupt worsening of a previously nonprogressive movement disorder. The movements became continuous, requiring artificial respiration and continuous sedation in the intensive‐care unit. Various drugs and drug combinations failed to achieve control. The child was then treated successfully with bilateral pallidal (GPi) stimulation as shown in the videotape. Four months later and without medication, the boy regained autonomous gait and audible speech; his neurologic condition continues to improve.
Url:
DOI: 10.1002/1531-8257(200009)15:5<1010::AID-MDS1039>3.0.CO;2-5
Affiliations:
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Le document en format XML
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<term>Critically ill</term>
<term>Deep brain stimulation</term>
<term>Diagnosis, Differential</term>
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<term>Dyskinesia</term>
<term>Dyskinesias (etiology)</term>
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<term>Dystonic Disorders (physiopathology)</term>
<term>Dystonic Disorders (therapy)</term>
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<term>Electrical stimulus</term>
<term>Electrodes, Implanted</term>
<term>Evolution</term>
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<term>Instrumentation therapy</term>
<term>Male</term>
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<term>Refractory dyskinesia</term>
<term>Refractory dystonia</term>
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<term>Stereotaxic Techniques</term>
<term>Treatment Outcome</term>
<term>Videotape Recording</term>
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<term>Dysarthria</term>
<term>Dyskinesias</term>
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<term>Diagnosis, Differential</term>
<term>Electrodes, Implanted</term>
<term>Humans</term>
<term>Male</term>
<term>Severity of Illness Index</term>
<term>Stereotaxic Techniques</term>
<term>Treatment Outcome</term>
<term>Videotape Recording</term>
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<term>Dyskinésie</term>
<term>Dystonie</term>
<term>Enfant</term>
<term>Etude cas</term>
<term>Evolution</term>
<term>Malade état grave</term>
<term>Mâle</term>
<term>Pallidum</term>
<term>Réfractaire</term>
<term>Stimulus électrique</term>
<term>Traitement instrumental</term>
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<front><div type="abstract" xml:lang="en">We report a 13‐year‐old boy who developed severe, refractory dystonia–dyskinesias as an abrupt worsening of a previously nonprogressive movement disorder. The movements became continuous, requiring artificial respiration and continuous sedation in the intensive‐care unit. Various drugs and drug combinations failed to achieve control. The child was then treated successfully with bilateral pallidal (GPi) stimulation as shown in the videotape. Four months later and without medication, the boy regained autonomous gait and audible speech; his neurologic condition continues to improve.</div>
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<affiliations><list><country><li>Italie</li>
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<tree><country name="Italie"><noRegion><name sortKey="Angelini, Lucia" sort="Angelini, Lucia" uniqKey="Angelini L" first="Lucia" last="Angelini">Lucia Angelini</name>
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<name sortKey="Broggi, Giovanni" sort="Broggi, Giovanni" uniqKey="Broggi G" first="Giovanni" last="Broggi">Giovanni Broggi</name>
<name sortKey="Conti, Chiara" sort="Conti, Chiara" uniqKey="Conti C" first="Chiara" last="Conti">Chiara Conti</name>
<name sortKey="Dones, Ivano" sort="Dones, Ivano" uniqKey="Dones I" first="Ivano" last="Dones">Ivano Dones</name>
<name sortKey="Estienne, Margherita" sort="Estienne, Margherita" uniqKey="Estienne M" first="Margherita" last="Estienne">Margherita Estienne</name>
<name sortKey="Nardocci, Nardo" sort="Nardocci, Nardo" uniqKey="Nardocci N" first="Nardo" last="Nardocci">Nardo Nardocci</name>
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